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KMID : 0377619640070030323
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Korean Jungang Medical Journal
1964 Volume.7 No. 3 p.323 ~ p.328
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A Case of Giant-Cell Pneumonia without Clinical Signs of Measles.
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李中仁/Lee, C.I.
吳成龍/李有福/徐世模/Oh, S.Y./Lee, Y.B./Shu, S.M.
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Abstract
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A case of giant-cell pneumonia developed in a 16 month old girl who had complaints of diarrhea, fever, and cough is reported.
The histopathologic picture of the lungs was the presence of multinucleated giant cells with intracytoplasmic and intranuclear inclusion bodies, in alveolar and bronchiolar lumina, with mononuclear cell infiltration, red blood cells and fibrin, interstitial edema and proliferation of interstitial tissue, and frequent squamous metaplasia of bronchiolar epithelium. These findings were essentially identical with those -cases reported in the literature. The lymphoid tissue in the ileum and colon showed marked reactive hyperplasia with a few rather small multinucleated giant cells containing intranuclear inclusion bodies, associated with superficial erosion. This is likely a part of main disease process, and account for diarrhea in this patient.
Causal agent in giant-cell pneumonia is reviewed, and the relationship between measles and giant-cell pneumonia is discussed. The altered or depressed immunologic response to the virus appears to play an important role in the development of giant-cell pneumonia.
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KEYWORD
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